Antidepressants, commonly used to treat anxiety, pain, or other disorders may play a role in dental implant failures, a pilot study at University of Buffalo School of Dental Medicine found.
The use of antidepressants increased the odds of implant failure by four times. After analyzing data from medical charts of UB Dental Clinic patients in 2014, the researchers found that of the patients who experienced implant failures, 33% used anti-depressants. For patients who did not experience failures, only 11% used the drugs.
While the drugs are often used to manage mood and emotions, the side effects of decrease in regulation of bone metabolism, osteoporosis, bruxism, and dry mouth all could affect the implant healing process.
More than 1 in 10 Americans over the age of 12 use antidepressants, making it the second most prescribed type of drug in the U. S. If you are one of these, patients you should ask your medical doctor about the side effects before considering a dental implant.
The researchers plan to build on the pilot study by retesting their results on a larger scale.
Patients should cooperate with both their physician and dentist to reach the right balance for optimal health.
This study was funded by the Student Research Program of UB and under the mentorship of Latifa Bairam, DDS, MS, and under the direction of Sebastiano Andreana, DDS, MS, and Mine Tezal, PhD, DDS in their Department of Oral Biology.
Inside Dentistry, May, 2016